Question of the Day – Tuesday December 11, 2018

Question – What class of cancer chemotherapeutic agents are the most common implicated in causing nail toxicity?

Answer – According to the cited article, “Taxanes are probably the most common class of cancer chemotherapeutic agents implicated in causing nail toxicity. The incidence of nail changes reported in early studies range from 0% to 44%, with the majority referring to docetaxel.” (Gilbar P et al. Nail toxicity induced by cancer chemotherapy. 2009 J Oncol Pharm Practice 15:143-155)