Question of the Day – Tuesday, August 9, 2022

Tricholoroethylene hypersensitivity syndrome (THS) has widespread effects including multisystem organ failure. What is the reported case fatality rate? Kamihima M et al. report Occupational trichloroethylene exposures resulting in THS in a subset of patients. The case fatality rate was 9-13%. Kamijima M, Hisanaga N, Wang…

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Question of the Day – Monday, August 8, 2022

Which indicators predict ADH failure in patients with ethylene glycol poisoning treated without extracorporeal treatment? In a recent systematic review by Beaulieu J et al., 96 articles yielding 411 cases, the ethylene glycol dose, adverse outcomes and treatment failures from EG poisoning were mostly described…

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Question of the Day – Friday, August 5, 2022

In a recent publication, this novel ‘nitazene’ was recently identified in 3 patients at a single site over a three day period. Calello DP et al. recently reported 3 cases in a 3 day period of N-piperidinyl etonitazene. This novel nitazene had not yet been…

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Question of the Day – Thursday, August 4, 2022

This is the base structure of this class of drugs? Benzimidazole. (Other name: Nitazenes). Small structural modifications at the R-groups produce a series of analogous structures such as isotonitazene, etonitazene and metonitazene, just to name a few. https://en.wikipedia.org/wiki/List_of_benzimidazole_opioids

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Question of the Day – Wednesday, August 3, 2022

In a recent study in 414 patients with caustic ingestion, what were independent predictors of survival? Assalino M et al. evaluated the outcomes of 414 patients between 2013-2019 with caustic ingestions particularly evaluating the role of CT versus endoscopy. In a multivariate analysis, intentional ingestion,…

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Question of the Day – Tuesday, August 2, 2022

In a recent study of therapeutic APAP dosing looking at protein adduct formation, what was the major difference between females and males? Arnold CG et al. performed a secondary analysis in subjects receiving 4 grams APAP daily for greater than or equal to 16 days…

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Question of the Day – Monday, August 1, 2022

In a prospective study from 2018 comparing low dose versus standard dose CT scan in body stuffers, what was the outcome? This study found that low dose CT scans were able to detect 100% of baggies that were larger than 1cm. Because of the small…

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Question of the Day – Friday, July 29, 2022

In a review article from 2019, a treatment algorithm was developed for the management of body stuffers; What role, if any, does whole bowel irrigation play in the management of these patients? According to the algorithm, there is no role for whole bowel irrigation and…

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Question of the Day – Thursday, July 28, 2022

In a cohort study of 132 body packers and stuffers what was concluded about the average length of stay? Length of say on average is 2 days before complete elimination of the drug packages. Heymann-Maier L, Trueb L, Schmidt S, Carron PN, Hugli O, Heymann…

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Question of the Day – Wednesday, July 27, 2022

In the observational prospective study titled “Complications and hospital stay after endoscopic retrieval of drug baggies in body stuffers: an observational prospective study” what was the most frequent drug encountered in the conservative group? Methamphetamine Shabani M, Kefayati M, Hassanian-Moghaddam H, Zamani N, McDonald R….

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