What is another name for methylene chloride, a common cause of neurologic, GI, and hepatorenal injuries in automotive/industrial workers? What is it metabolized to, and by what?
Dichloromethane, metabolized to carbon monoxide via CYP 2E1.
Jaffe TA, Boyer EW, Erickson TB, Studley H, Hayes BD, Chai PR. Acute and delayed toxicity from co-ingestion of methylene chloride and methanol. Toxicology Communications. 2019;3(1):79-84. doi:10.1080/24734306.2019.1685222
Contributed by: Toxikon Fellowship
Posted in Question Of The Day