Question - Overdose involving which drugs was first reported in the emergency medicine literature to be successfully treated with intravenous lipid emulsion therapy?
Answer- The cited editorial notes “After the initial report of treatment of bupropion and lamotrigine overdose by intravenous lipid emulsion, additional case reports have asserted the usefulness of lipid emulsion for enteral poisonings.” (Sirianni AJ et al. Use of lipid emulsion in the resuscitation of a patient with prolonged cardiovascular collapse after overdose of buproprion and lamotrigine. 2008 Ann Emerg Med 51:412-415 as cited in Fettiplace MR et al. Confusion about infusion: Rational volume limits for intravenous lipid emulsion during treatment of oral overdoses. 2015 Ann Emerg Med 66(2): 185-187.)