In a 2023 retrospective case control study, what was the incidence of disulfiram-like reactions in patients who received metronidazole and ethanol concurrently as compared to control group (ethanol only)?
There was no increase in incidence of disulfiram-like reaction in metronidazole group.
Feldman R, Jaszczenski R. Can Metronidazole Cause a Disulfiram-Like Reaction? A Case-Control Study Propensity Matched by Age, Sex, and Ethanol Concentration. WMJ. 2023;122(3):171-177.
Contributed by: Erin Smith, MD, PGY3 Emergency Medicine Resident, Jackson Memorial Hospital on behalf of the Florida Poison Information Center Network
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