Question - What characterizes cutaneous reactions to bed bug (Cimex lectularius) bites?
Answer - One review reported “Our review of case reports revealed that the usual response to a bed bug bite appears to be no reaction with a barely visible punctum at the location of the bite. The most common reactions for which medical attention is sought are 2- to 5-mm pruritic maculopapular, erythematous lesions at bed bug feeding sites, one per insect. These usually itch and, if not abraded, resolve within a week. The size and pruritus associated with these common reactions may increase in some individuals who experience repeated bites. There are no data to establish how frequently common reactions occur.” (Goddard J and deShazo R. Bed bugs (Cimex lectularius) and clinical consequences of their bites. 2009 JAMA 301(13): 1358-1366)