Question - What is the effect of high ambient temperature on mortality from cocaine overdose?
Answer - One study reports “A threshold temperature of 31.1°C (88°F) was identified, above which the mean daily number of fatal cocaine overdoses increased steadily. On days with a maximum daily temperature of 31.1°C (88°F) or higher ("hot days"), the mean daily number of cocaine overdose deaths was 2.34 (SD=1.68), which was 33% higher than the mean on days with a maximum temperature of less than 31.1°C (88°F) (mean=1.76 [SD=1.37] (P<.001).” (Marzuk PM et al. Ambient temperature and mortality from unintentional cocaine overdose. 1998 JAMA 279(22):1795-1800)