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January 31, 2024

Question of the Day – Wednesday, January 31, 2024

Both the hooded pithoui bird and neotropical frogs from the genus Phyllobates concentrate batrachotoxins. While contact with these frogs can cause severe symptoms, exposures from birds are milder. What is the most likely reason for the observed difference?

According to the cited reference the most likely explanation is that birds carry lower concentrations of toxin as compared with dendrobatid frogs

Dumbacher JP, Beehler BM, Spande TF, Garrafo HM, Daly JW. Homobatrachotoxin in the Genus Pitohui: Chemical Defense in Birds? Science. 1992;258(5083):799–801. https://doi.org/10. 1126/science.1439786.

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