Skip to content
The American Academy of Clinical Toxicology
  • Education & Groups
    • American Board of Applied Toxicology (ABAT)
      • 2025 ABAT Election Ballot
      • ABAT Travel Grant
      • ABAT Exceptional Service Award
      • ABAT Newsletter
      • Sitting for the American Board of Applied Toxicology Exam
        • ABAT Examination Study Guide
      • Certification Renewal Documents
      • Life Long Learning Articles (LLSA)
      • ABAT Member Directory
        • Diplomate Verification
      • ABAT Board of Directors Contact Information
    • AACT Antidote Collective
    • E-Learning
      • Research Seminar: The Nuts and Bolts of Toxicology Research
      • Advanced Hazmat Life Support Training
      • TOXISMO Society for the Discussion of Scientific Literature
      • ToxNow
      • Webinars
        • ABAT Journal Club Webinars
        • COVID Webinar Series
    • Toxicology Residency & Fellowship Training Programs
    • Clinical Toxicology Guidelines Collaborative
      • Recommendations
    • ToxCoach Mentorship Program
    • Committees
      • AACT Committee Leadership Opportunities
    • Sections
      • Acute & Intensive Care
      • Addiction Toxicology Section
      • Clinical Toxicology In Sports
      • Diversity, Equity, and Inclusion Section
      • Herbs & Dietary Supplements
      • Geriatric Toxicology
      • Occupational / Environmental
      • Envenomations
      • Forensic
      • Pediatric
      • Weapons of Mass Destruction
      • Toxicology History
      • Radiation
      • Trainee and Student
    • Student Chapters
    • National Clintox Book Club
    • Webinars
  • NACCT Annual Meeting
    • Abstract Submissions
    • Meeting Information
    • Register
    • After the Fact CE
  • Research Grants
    • AACT Research Award
    • AACT Knowledge Translation Grant Award
    • Junior Investigator Research Grant
    • Gary S. Wasserman, DO, FAACT Memorial Pediatric Abstract Award
    • Toxicology Trainee Research Grant
    • Student and Trainee Travel Award
    • Lampe-Kunkel Memorial Award
  • Resources
    • Event Calendar
    • Publications
      • Clinical Toxicology Journal
      • Question of the Day
      • News
      • Current Awareness in Clinical Toxicology
      • Toxicology Today
      • Out of Hospital Guidelines
    • Toxicology Information
    • Affiliated Organizations
    • Press Resources
    • Job Opportunities
    • Online Store
  • About Us
    • Board of Trustees
      • AACT Board of Trustees Nominations
    • Mission & Strategic Plan
    • Bylaws
    • AACT Code of Ethics
    • Our History
    • Fellows of AACT
    • Membership
      • AACT Member Directory
    • Award Recipients
    • Contact Us
  • Contact Us
  • Renew
  • Donate
  • Journal Access
The American Academy of Clinical Toxicology
Member LoginJoinContact
  • Education & Groups
    • American Board of Applied Toxicology (ABAT)
      • 2025 ABAT Election Ballot
      • ABAT Travel Grant
      • ABAT Exceptional Service Award
      • ABAT Newsletter
      • Sitting for the American Board of Applied Toxicology Exam
        • ABAT Examination Study Guide
      • Certification Renewal Documents
      • Life Long Learning Articles (LLSA)
      • ABAT Member Directory
        • Diplomate Verification
      • ABAT Board of Directors Contact Information
    • AACT Antidote Collective
    • E-Learning
      • Research Seminar: The Nuts and Bolts of Toxicology Research
      • Advanced Hazmat Life Support Training
      • TOXISMO Society for the Discussion of Scientific Literature
      • ToxNow
      • Webinars
        • ABAT Journal Club Webinars
        • COVID Webinar Series
    • Toxicology Residency & Fellowship Training Programs
    • Clinical Toxicology Guidelines Collaborative
      • Recommendations
    • ToxCoach Mentorship Program
    • Committees
      • AACT Committee Leadership Opportunities
    • Sections
      • Acute & Intensive Care
      • Addiction Toxicology Section
      • Clinical Toxicology In Sports
      • Diversity, Equity, and Inclusion Section
      • Herbs & Dietary Supplements
      • Geriatric Toxicology
      • Occupational / Environmental
      • Envenomations
      • Forensic
      • Pediatric
      • Weapons of Mass Destruction
      • Toxicology History
      • Radiation
      • Trainee and Student
    • Student Chapters
    • National Clintox Book Club
    • Webinars
  • NACCT Annual Meeting
    • Abstract Submissions
    • Meeting Information
    • Register
    • After the Fact CE
  • Research Grants
    • AACT Research Award
    • AACT Knowledge Translation Grant Award
    • Junior Investigator Research Grant
    • Gary S. Wasserman, DO, FAACT Memorial Pediatric Abstract Award
    • Toxicology Trainee Research Grant
    • Student and Trainee Travel Award
    • Lampe-Kunkel Memorial Award
  • Resources
    • Event Calendar
    • Publications
      • Clinical Toxicology Journal
      • Question of the Day
      • News
      • Current Awareness in Clinical Toxicology
      • Toxicology Today
      • Out of Hospital Guidelines
    • Toxicology Information
    • Affiliated Organizations
    • Press Resources
    • Job Opportunities
    • Online Store
  • About Us
    • Board of Trustees
      • AACT Board of Trustees Nominations
    • Mission & Strategic Plan
    • Bylaws
    • AACT Code of Ethics
    • Our History
    • Fellows of AACT
    • Membership
      • AACT Member Directory
    • Award Recipients
    • Contact Us
  • Contact Us
February 2, 2022

Question of the Day – Wednesday, February 2, 2022

Calcium carbide is used industrially as a welding agent due to the liberation of flammable acetylene gas on contact with moisture. It is included in the Toxic Substances Control Act (TSCA) Chemical Substance Inventory of the Environmental Protection Agency (EPA). Industrial acetylene gas behaves as a simple asphyxiant which affects the neurological system by causing prolonged hypoxia. In developing countries, calcium carbide is illegally used as an artificial ripening agent as the acetylene gas is an ethylene analogue which is a naturally occurring ripening agent produced by fruits. What other potential toxicities may be involved in this process?

Despite its ban by the South Asian Association for Regional Co-operation (SAARC), there is no policy/guideline on fruit agriculture in developing countries. Calcium carbide manufacturing can often get contaminated with heavy metals such as arsenic and phosphorous which can result in liberation of arsine and phosphine gas. These impurities can be removed by driving acetylene gas through acidified copper sulfate solution, unfortunately, in under-resourced settings, this step is ignored. Fruits ripened with calcium carbide exhibit the least organoleptic quality compared to naturally ripened fruits. The fruit may develop an attractive surface color but the tissue inside may be unripe. A very raw fruit would require greater amounts of calcium carbide making it highly toxic. Consumers should thoroughly wash and peel off the fruits so that surface chemicals are removed.

Contributor: Muhammad Akbar Baig, MD, Northshore University Medical Toxicology Fellowship

1) Islam, M.N., Mursalat, M. & Khan, M.S. A review on the legislative aspect of artificial fruit ripening. Agric & Food Secur 5, 8 (2016). doi.org/10.1186/s40066-016-0057-5. 2) Maduwanthi SDT, Marapana RAUJ. Induced Ripening Agents and Their Effect on Fruit Quality of Banana. Int J Food Sci. 2019 May 2;2019:2520179. doi: 10.1155/2019/2520179. PMID: 31187037; PMCID: PMC6521425. 3) Per H, Kurtoğlu S, Yağmur F, Gümüş H, Kumandaş S, Poyrazoğlu MH. Calcium carbide poisoning via food in childhood. J Emerg Med. 2007 Feb;32(2):179-80. doi: 10.1016/j.jemermed.2006.05.049. Epub 2007 Jan 22. PMID: 17307629.

Posted in Question Of The Day
Share this

Recent Posts

  • Question of the Day – Monday, November 4, 2024
  • Question of the Day – Friday, November 1, 2024
  • Question of the Day – Thursday, October 31, 2024
  • Question of the Day – Wednesday, October 30, 2024
  • Question of the Day – Tuesday, October 29, 2024

Site Search

Get Involved

Volunteer for a committee, as a section chair, student chapter mentor, author Question of the Day and more!

Volunteer

Support AACT

Become a ‘Friend of the Academy’ through a tax-deductible financial contribution. Donating is just a text away!

Make a Contribution
aact-footer-logo

American Academy of Clinical Toxicology
1061 East Main Street, Suite 300
East Dundee, Illinois 60118
847-752-9365

Proudly Managed by
Veritas Logo

LinkedIn Twitter/X Facebook Bluesky

Privacy Policy

  • Education & Groups
    • American Board of Applied Toxicology (ABAT)
      • 2025 ABAT Election Ballot
      • ABAT Travel Grant
      • ABAT Exceptional Service Award
      • ABAT Newsletter
      • Sitting for the American Board of Applied Toxicology Exam
        • ABAT Examination Study Guide
      • Certification Renewal Documents
      • Life Long Learning Articles (LLSA)
      • ABAT Member Directory
        • Diplomate Verification
      • ABAT Board of Directors Contact Information
    • AACT Antidote Collective
    • E-Learning
      • Research Seminar: The Nuts and Bolts of Toxicology Research
      • Advanced Hazmat Life Support Training
      • TOXISMO Society for the Discussion of Scientific Literature
      • ToxNow
      • Webinars
        • ABAT Journal Club Webinars
        • COVID Webinar Series
    • Toxicology Residency & Fellowship Training Programs
    • Clinical Toxicology Guidelines Collaborative
      • Recommendations
    • ToxCoach Mentorship Program
    • Committees
      • AACT Committee Leadership Opportunities
    • Sections
      • Acute & Intensive Care
      • Addiction Toxicology Section
      • Clinical Toxicology In Sports
      • Diversity, Equity, and Inclusion Section
      • Herbs & Dietary Supplements
      • Geriatric Toxicology
      • Occupational / Environmental
      • Envenomations
      • Forensic
      • Pediatric
      • Weapons of Mass Destruction
      • Toxicology History
      • Radiation
      • Trainee and Student
    • Student Chapters
    • National Clintox Book Club
    • Webinars
  • NACCT Annual Meeting
    • Abstract Submissions
    • Meeting Information
    • Register
    • After the Fact CE
  • Research Grants
    • AACT Research Award
    • AACT Knowledge Translation Grant Award
    • Junior Investigator Research Grant
    • Gary S. Wasserman, DO, FAACT Memorial Pediatric Abstract Award
    • Toxicology Trainee Research Grant
    • Student and Trainee Travel Award
    • Lampe-Kunkel Memorial Award
  • Resources
    • Event Calendar
    • Publications
      • Clinical Toxicology Journal
      • Question of the Day
      • News
      • Current Awareness in Clinical Toxicology
      • Toxicology Today
      • Out of Hospital Guidelines
    • Toxicology Information
    • Affiliated Organizations
    • Press Resources
    • Job Opportunities
    • Online Store
  • About Us
    • Board of Trustees
      • AACT Board of Trustees Nominations
    • Mission & Strategic Plan
    • Bylaws
    • AACT Code of Ethics
    • Our History
    • Fellows of AACT
    • Membership
      • AACT Member Directory
    • Award Recipients
    • Contact Us
  • Contact Us

© 2025 American Academy of Clinical Toxicology | Sitemap

Website by Yoko Co

Scroll To Top