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December 15, 2021

Question of the Day – Wednesday December 15, 2021

It has been noted that the residual calculated osmolal gap increases with increasing ethanol levels. Purssell et al. found that there is a linear relationship between the serum ethanol level and the osmolal gap. What do they suggest the multiplicative factor for ethanol in formulas to calculate serum osmolarity be?

Purssell et al. findings suggest that each millimole of ethanol contributes 1.25 mOsm to serum osmolarity and that the multiplicative factor for ethanol in formulas should be 0.27 (1/3.7) or 1.25 if using SI units.

Purssell RA et al. Derivation and Validation of a Formula to Calculate the Contribution of Ethanol to the Osmolal Gap. Ann Emerg Med 2001; 38(6): 653-659. https://doi.org/10.1067/mem.2001.119455

 

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  • Education & Groups
    • American Board of Applied Toxicology (ABAT)
      • ABAT Exceptional Service Award
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      • Sitting for the American Board of Applied Toxicology Exam
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      • ABAT Member Directory
        • Diplomate Verification
      • ABAT Board of Directors Contact Information
    • E-Learning
      • Advanced Hazmat Life Support Training
      • MMTI Fundamentals for Front-Line Practitioners Training
      • TOXISMO Society for the Discussion of Scientific Literature
      • ToxNow
      • Webinars
        • ABAT Journal Club Webinars
        • COVID Webinar Series
    • Toxicology Residency & Fellowship Training Programs
    • Clinical Toxicology Guidelines Collaborative
      • Recommendations
    • Fellows of AACT
    • ToxCoach Mentorship Program
    • Committees
    • Sections
      • Acute & Intensive Care
      • Addiction Toxicology Section
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