Question - What is the gold standard for the diagnosis of skeletal fluorosis?
Answer- The cited article notes “…..a bone biopsy with quantitative bone ash fluoride analysis remains the gold standard for the diagnosis of skeletal fluorosis.” (Cohen E, Hsu RY, Evangelista P, Aaron R, Rubin LE. Rapid-onset diffuse skeletal fluorosis from inhalant abuse: a case report. JBJS Case Connector. 2014;4(4):e108. As cited in Eggleston W and Nelson LS. He huffed and he puffed and he got frostbite. 2016 (June) www.emed-journal.com. DOI: 10.12788/emed.2016.0036; 267-269)