Why are newborns more susceptible to the development of methemoglobin?
Newborns have a lower activity of cytochrome b5 reductase, estimated to be 50-60% of adult values.
Raucci U et al. Acquired methemoglobinemia in children presenting to Italian pediatric emergency departments: A multicenter report. Clin Tox. Published online 13 April 2022. doi/full/10.1080/15563650.2022.2061986