Seizures and sympathomimetic effects are well-described after bupropion toxicity. This effect, however, is more controversial.
In a recent retrospective analysis of single agent bupropion exposures, 13 patients (5.9%) were diagnosed with serotonin toxicity. (Murray B et al. Single Agent Bupropion exposures: Clinical characteristics and an atypical cause of serotonin toxicity. JMT 2020; 16(1): 12-16. doi: 10.1007/s13181-019-00749-4.)