Tetramethylammonium hydroxide (TMAH) is a cholinergic agonist that can cause rapid respiratory failure and death. What are the industrial uses of TMAH?
TMAH is a chemical used to etch silicon in the development of electronic devices. Previous industrial exposures to high concentration products (25%) have led to rapid respiratory failure and death. This risk appears to be higher in patients who develop second- or third-degree burns due to TMAH’s alkaline corrosive properties.
Lin C-C et al. Tetramethylammonium hydroxide poisoning. Clin Tox 2010; 48(3): 213-217