In retrospective review of NPDS data, how did the epidemiology of fatal verapamil and amlodipine toxicity change from 2011 to 2020?
In 2011, there were 32 fatal verapamil overdoses and 26 fatal amlodipine overdoses. In 2020, verapamil accounted for 25 fatalities while amlodipine accounted for 82 fatalities.
Cole JB, Lee SC, Prekker ME, Kunzler NM, Considine KA, Driver BE, Puskarich MA, Olives TD. Vasodilation in patients with calcium channel blocker poisoning treated with high-dose insulin: a comparison of amlodipine versus non-dihydropyridines. Clin Toxicol (Phila). 2022 Nov;60(11):1205-1213. doi: 10.1080/15563650.2022.2131565. Epub 2022 Oct 25. PMID: 36282196.