According to a recent retrospective review of opioid-associated hearing loss, the majority of cases occurred after exposure to what agent?
According to the cited reference, the majority of cases occurred after exposure to heroin (51%, n=22), although ototoxicity occurs across the entire class of opioid agonists. The authors note that ototoxicity occurs irrespective of hypoxia, with only 34% of cases associated with a potential hypoxic event.
Mozeika, A.M., Ruck, B.E., Nelson, L.S. et al. Opioid-Associated Hearing Loss: A 20-Year Review from the New Jersey Poison Center. J. Med. Toxicol. 16, 416–422 (2020). https://doi.org/10.1007/s13181-020-00785-5