According to an observational cohort study of 5,784 patients who received droperidol in an academic emergency department, what was the incidence of akathisia?
The authors did not find akathisia or dystonia coded in the electronic dataset. Among 796 independently reviewed charts, 2.9% (N = 23) of cases had akathisia. All cases resolved with diphenhydramine. In this study, QT prolongation was rare and there were no clinically significant arrhythmias or death attributable to droperidol
Gaw CM, Cabrera D, Bellolio F, Mattson AE, Lohse CM, Jeffery MM. Effectiveness and safety of droperidol in a United States emergency department. Am J Emerg Med. 2020 Jul;38(7):1310-1314. doi: 10.1016/j.ajem.2019.09.007. Epub 2019 Nov 25. PMID: 31831345.
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