Question - While envenomation from copperhead snake bites rarely cause systemic effects a substantial number of bite victims of this snake suffer significant pain and swelling of the envenomated limb. What percent of copperhead bite victims develop significant pain and swelling of the envenomated limb?
Answer - The cited article reports that “More than 95% of copperhead victims develop significant pain and swelling of the envenomated limb, but systemic venom effects are uncommon and death is rare.” (Gerardo CF, et al. The efficacy of crotalidae polyvalent immuneFab (ovine) antivenin versus placebo plus optional rescue therapy on recovery from copperhead snake envenomation: A randomize, double-blind, placebo-controlled, clinical trial. 2017 Ann Emerg Med 70(2): 233-244)