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October 15, 2018

Question of the Day – Monday October 15, 2018

Question -Hydroxyurea (hydrooxycarbamide) is an antineoplastic drug sometimes used in the treatment of myeloproliferative disorders as well as in a variety of malignancies. The most common toxicities attributed to the use of this drug include bone marrow failure and associated pancytopenia. What are the potential pulmonary toxicities associate with the use of this drug?

Answer- The cited article notes that “hydroxycarbamide can induce lung toxicity with pulmonary edema and lung infiltration” with resultant pulmonary fibrosis. (Bargagli E., et al. Fibrotic lung toxicity induced by hydroxycarbamide. 2017 In Vivo. 31:1221-1223)

Question 1-Hydroxyurea (hydrooxycarbamide) is an antineoplastic drug sometimes used in the treatment of myeloproliferative disorders as well as in a variety of malignancies. The most common toxicities attributed to the use of this drug include bone marrow failure and associated pancytopenia. What are the potential pulmonary toxicities associate with the use of this drug?

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  • Education & Groups
    • American Board of Applied Toxicology (ABAT)
      • ABAT Exceptional Service Award
      • ABAT Newsletter
      • Sitting for the American Board of Applied Toxicology Exam
        • ABAT Examination Study Guide
      • Certification Renewal Documents
      • Life Long Learning Articles (LLSA)
      • ABAT Member Directory
        • Diplomate Verification
      • ABAT Board of Directors Contact Information
    • E-Learning
      • Advanced Hazmat Life Support Training
      • MMTI Fundamentals for Front-Line Practitioners Training
      • TOXISMO Society for the Discussion of Scientific Literature
      • ToxNow
      • Webinars
        • ABAT Journal Club Webinars
        • COVID Webinar Series
    • Toxicology Residency & Fellowship Training Programs
    • Clinical Toxicology Guidelines Collaborative
      • Recommendations
    • Fellows of AACT
    • ToxCoach Mentorship Program
    • Committees
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      • Acute & Intensive Care
      • Addiction Toxicology Section
      • Clinical Toxicology In Sports
      • Diversity, Equity, and Inclusion Section
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