Question - What serious immune system reaction regarding the drug lamotrigine has recently been warned by the FDA?
Answer - The immune system reaction associated with lamotrigine is called hemophagocytic lymphohistiocytosis (HLH) and causes an uncontrolled response by the immune system. HLH typically presents as a persistent fever, usually greater than 101°F, and it can lead to severe problems with blood cells and organs throughout the body such as the liver, kidneys, and lungs. (https://www.fda.gov/safety/medwatch/safetyinformation/safetyalertsforhumanmedicalproducts/ucm605628.htm;Accessed April 2018)
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