In a recent study, what was one of the differences of F(AB’)-2 compared to FAB?
a. Increased immediate allergic reactions in the F(AB’)-2 group
b. Higher rate of type III hypersensitivity reactions in the F(AB’)-2 group compared to FAB group.
c. Increased persistent, recurrent or late-new-onset hematologic abnormalities in the F(AB’)-2 group compared to FAB group.
Answer B. Mascarenas DN et al. reported an overall higher rate of Type III hypersensitivity reactions in the F(AB’)-2 group compared to FAB group.
Mascarenas DN et al. Comparison of F(ab’)2 and Fab antivenoms in rattlesnake envenomation: First year’s post-marketing experience with F(ab’)2 in New Mexico. Toxicon 2020; 186: 42-45.
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