Historical QOD 4/3/09: Para-chloroaniline is found as a product in the dye, pharmaceutical and herbicide industries. What is the primary potential health threat from p-chloroaniline following unprotected exposure for workers in these settings?
P-chloroaniline is a potent methemoglobin inducer. In fact, p- chloroaniline is reportedly more potent at producing methemoglobinemia than aniline itself in animal models.
Pizon AF, et al.2009. Clinical Toxicology 47(2):132-136
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