What is Rossolimo’s sign, and chronic abuse of which drug is it associated with?
Rossolimo’s sign is a physical examination finding where percussion of the tips of the toes results in exaggerated flexion of the toes. It has been reported in association with nitrous oxide abuse.
Blanco G, Peters HA. Myeloneuropathy and Macrocytosis Associated With Nitrous Oxide Abuse. Arch Neurol. 1983;40(7):416–418. doi:10.1001/archneur.1983.04050070046009