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August 22, 2022

Question of the Day – Monday, August 22, 2022

A patient ingests ceramic glaze in an attempt to harm and presents to the Emergency Department approximately 2 hours later with nausea, vomiting, diarrhea and weakness. What laboratory test will help confirm the diagnosis?

Serum potassium. Barium carbonate, hydroxide and chloride are used in the production of ceramics. Barium toxicity typically occurs within 2 hours after ingestion. Barium competitively antagonizes the inward rectifier potassium channels and increases sodium/potassium ATPase activity resulting in an increase in intracellular potassium and subsequent hypokalemia.

Jamshidi N et al. Life-threatening barium carbonate poisoning managed with intravenous potassium, continuous veno-venous hemodialysis and endoscopic removal of retained ceramic glazes. Clin Tox Published online 4 May 2022. https://doi.org/10.1080/15563650.2022.2068424

Posted in Question Of The Day
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  • Education & Groups
    • American Board of Applied Toxicology (ABAT)
      • ABAT Exceptional Service Award
      • ABAT Newsletter
      • Sitting for the American Board of Applied Toxicology Exam
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      • Certification Renewal Documents
      • Life Long Learning Articles (LLSA)
      • ABAT Member Directory
        • Diplomate Verification
      • ABAT Board of Directors Contact Information
    • E-Learning
      • Advanced Hazmat Life Support Training
      • MMTI Fundamentals for Front-Line Practitioners Training
      • TOXISMO Society for the Discussion of Scientific Literature
      • ToxNow
      • Webinars
        • ABAT Journal Club Webinars
        • COVID Webinar Series
    • Toxicology Residency & Fellowship Training Programs
    • Clinical Toxicology Guidelines Collaborative
      • Recommendations
    • Fellows of AACT
    • ToxCoach Mentorship Program
    • Committees
    • Sections
      • Acute & Intensive Care
      • Clinical Toxicology In Sports
      • Diversity, Equity, and Inclusion Section
      • Herbs & Dietary Supplements
      • Geriatric Toxicology
      • Occupational / Environmental
      • Envenomations
      • Forensic
      • Pediatric
      • Weapons of Mass Destruction
      • Toxicology History
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    • Student Chapters
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