Question - What are so-called “cocaine-induced midline destructive lesions (CIMDL)”?
Answer- The cited article notes “Cocaine-induced midline destructive lesions (CIMDL) are one of the most frequent mucocutaneous manifestations of cocaine abuse, and are due to drug-induced chronic rhinitis, which leads to inflammation and tissue destruction.” CIMDL consist of destruction of the midline facial structures and manifests as facial pain, epistaxis and chronic rhinitis. These authors note “Clinically, involvement of the nasal septum is a common and almost constant finding in patients with CIMDL…” (Moreno-Artero E. et al. Mucocutaneous manifestations of cocaine abuse: a review. 2018 JEADV 32:1420-1426)