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March 10, 2023

Question of the Day – Friday, March 10, 2023

Emerging evidence suggests that liver injury from some supplements may be immune mediated. Which herbal supplements has this been suggested recently?

HLA allele B*35:01 has been associated with drug induced liver injury from herbal supplements including: Green tea extract; turmeric and Garcinia cambogia.

1. Hoofnagle JH et al. HLA-B*35:01 and Green Tea-Induced Liver Injury. Hepatology 2021 Jun; 73(6): 2484-2493. PMID 32892374; 2. Vuppalanchi R et al. Garcinia cambogia, either alone or in combination with green tea, causes moderate to severe liver injury. Clin Gastroenterol Hepatol 2022 June 20(6): e1416-1425. PMID 34400337; 3. Halegoua-DeMarzio D et al. Liver Injury Associated with Turmeric-A Growing Problem: Ten Cases from the Drug Induced Liver Injury Network. Am J Med 2023 Feb; 136(2): 200-206. PMID 36252717.

 

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  • Education & Groups
    • American Board of Applied Toxicology (ABAT)
      • 2025 ABAT Election Ballot
      • ABAT Travel Grant
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      • Sitting for the American Board of Applied Toxicology Exam
        • ABAT Examination Study Guide
      • Certification Renewal Documents
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      • ABAT Member Directory
        • Diplomate Verification
      • ABAT Board of Directors Contact Information
    • AACT Antidote Collective
    • E-Learning
      • Research Seminar: The Nuts and Bolts of Toxicology Research
      • Advanced Hazmat Life Support Training
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      • ToxNow
      • Webinars
        • ABAT Journal Club Webinars
        • COVID Webinar Series
    • Toxicology Residency & Fellowship Training Programs
    • Clinical Toxicology Guidelines Collaborative
      • Recommendations
    • ToxCoach Mentorship Program
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      • AACT Committee Leadership Opportunities
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