In a recent case report of a patient hospitalized for treatment of chronic lower extremity wounds thought to be due to xylazine injection, what medications were used to treat symptoms which authors attributed to a withdrawal syndrome from xylazine?
Dexmedetomidine, tizanidine, phenobarbital, and clonidine. The patient was started on buprenorphine via microinduction and discharged with buprenorphine, clonidine, and gabapentin as adjunctive treatment for ongoing pain.
Ehrman-Dupre R, et. al. Management of Xylazine Withdrawal in a Hospitalized Patient: A Case Report. J Addict Med. 2022;16(5):595-598. doi:10.1097/ADM.0000000000000955
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