This vital sign abnormality was present in nearly 60% of patients with bupropion overdose?
Offerman et al. report 437 patients with bupropion overdose and tachycardia was present in 56.5% of patients and 50.6% of patients had sustained tachycardia. Among patients with tachycardia on arrival, the odds of the patient having a seizure at any point was 6.7 (CI 3.72-10.9) (Offerman S et al. Bupropion associated seizures following acute overdose: who develops late seizures. Clin Tox 2020; published online 3/26/2020. DOI: https://doi/org/10.1080/15563650.2020.1742919.)