Clonidine overdose can present in the same way as an overdose of what other class of medications?
Clonidine overdoses mimic that of opioid overdoses with signs of central nervous system depression, bradycardia, hypotension, and respiratory depression. Treatment options are also similar to that of opioid overdoses including fluids, vasopressors, naloxone, and intubation.
Isbister GK, Heppell SP, Page CB, Ryan NM. Adult clonidine overdose: prolonged bradycardia and central nervous system depression, but not severe toxicity. Clin Toxicol (Phila). 2017 Mar;55(3):187-192. doi: 10.1080/15563650.2016.1277234. Epub 2017 Jan 20. PMID: 28107093.
Contributed by: Emily Plasencia, PharmD on behalf of the Acute & Intensive Care