What administration counseling points should be given for patients taking oral bisphosphonates to mitigate what GI adverse reactions?
According to the cited reference, patients should be counseled to take medication with a full glass of water (6-8 oz.) and to remain upright for at least 30 minutes after ingestion to avoid GI ADE such as nausea, vomiting, epigastric pain and dyspepsia
Papapetrou, Peter. “Bisphosphonate-Associated Adverse Events.” HORMONES, vol. 8, no. 2, 2009, pp. 96–110, https://doi.org/10.14310/horm.2002.1226
Contributed by Vincent Gao, Pharm D candidate
Posted in Question Of The Day