Question - Dimethylformamide (DMF) is known to cause hepatotoxicity in workers exposed to this chemical. What liver toxicities have been reported to be associated with occupational exposure to DMF?
Answer- The cited article notes “The most prevalent disorders found in the workers exposed to DMF were liver toxicities, including hepatitis, fibrosis, cirrhosis, and cancer. Other symptoms, such as alcohol intolerance, possible embryotoxicity, and teratogenicity, were also found….” (Kim TH and Geon S. Clinical outcomes of occupational exposure to N,N-Dimethylformamide: Perspectives from experimental toxicology. 2011 Safe Health Work 2:97-104)