Skip to content
The American Academy of Clinical Toxicology
  • Education & Groups
    • American Board of Applied Toxicology (ABAT)
      • ABAT Exceptional Service Award
      • ABAT Newsletter
      • Sitting for the American Board of Applied Toxicology Exam
        • ABAT Examination Study Guide
      • Certification Renewal Documents
      • Life Long Learning Articles (LLSA)
      • ABAT Member Directory
        • Diplomate Verification
      • ABAT Board of Directors Contact Information
    • E-Learning
      • Advanced Hazmat Life Support Training
      • MMTI Fundamentals for Front-Line Practitioners Training
      • TOXISMO Society for the Discussion of Scientific Literature
      • ToxNow
      • Webinars
        • ABAT Journal Club Webinars
        • COVID Webinar Series
    • Toxicology Residency & Fellowship Training Programs
    • Clinical Toxicology Guidelines Collaborative
      • Recommendations
    • Fellows of AACT
    • ToxCoach Mentorship Program
    • Committees
    • Sections
      • Acute & Intensive Care
      • Addiction Toxicology Section
      • Clinical Toxicology In Sports
      • Diversity, Equity, and Inclusion Section
      • Herbs & Dietary Supplements
      • Geriatric Toxicology
      • Occupational / Environmental
      • Envenomations
      • Forensic
      • Pediatric
      • Weapons of Mass Destruction
      • Toxicology History
      • Radiation
      • Trainee and Student
    • Student Chapters
  • NACCT Annual Meeting
    • Meeting Information
    • Abstract Submissions
    • After the Fact CE
  • Research Grants
    • AACT Research Award
    • AACT Knowledge Translation Grant Award
    • Junior Investigator Research Grant
    • Gary S. Wasserman, DO, FAACT Memorial Pediatric Abstract Award
    • Toxicology Trainee Research Grant
    • Student and Trainee Travel Award
    • Lampe-Kunkel Memorial Award
  • Resources
    • Event Calendar
    • AACT Mobile App
    • Publications
      • AACTion
      • Abstracts
      • Clinical Toxicology Journal
      • Question of the Day
      • News
      • Current Awareness in Clinical Toxicology
      • Toxicology Today
      • Out of Hospital Guidelines
    • Toxicology Information
    • Affiliated Organizations
    • Press Resources
    • Job Opportunities
    • Online Store
  • About Us
    • Mission & Strategic Plan
    • Board of Trustees
    • Our History
    • Membership
      • AACT Member Directory
    • Award Recipients
    • Contact Us
  • Contact Us
  • Renew
  • Donate
  • Journal Access
The American Academy of Clinical Toxicology
Member LoginJoinContact
  • Education & Groups
    • American Board of Applied Toxicology (ABAT)
      • ABAT Exceptional Service Award
      • ABAT Newsletter
      • Sitting for the American Board of Applied Toxicology Exam
        • ABAT Examination Study Guide
      • Certification Renewal Documents
      • Life Long Learning Articles (LLSA)
      • ABAT Member Directory
        • Diplomate Verification
      • ABAT Board of Directors Contact Information
    • E-Learning
      • Advanced Hazmat Life Support Training
      • MMTI Fundamentals for Front-Line Practitioners Training
      • TOXISMO Society for the Discussion of Scientific Literature
      • ToxNow
      • Webinars
        • ABAT Journal Club Webinars
        • COVID Webinar Series
    • Toxicology Residency & Fellowship Training Programs
    • Clinical Toxicology Guidelines Collaborative
      • Recommendations
    • Fellows of AACT
    • ToxCoach Mentorship Program
    • Committees
    • Sections
      • Acute & Intensive Care
      • Addiction Toxicology Section
      • Clinical Toxicology In Sports
      • Diversity, Equity, and Inclusion Section
      • Herbs & Dietary Supplements
      • Geriatric Toxicology
      • Occupational / Environmental
      • Envenomations
      • Forensic
      • Pediatric
      • Weapons of Mass Destruction
      • Toxicology History
      • Radiation
      • Trainee and Student
    • Student Chapters
  • NACCT Annual Meeting
    • Meeting Information
    • Abstract Submissions
    • After the Fact CE
  • Research Grants
    • AACT Research Award
    • AACT Knowledge Translation Grant Award
    • Junior Investigator Research Grant
    • Gary S. Wasserman, DO, FAACT Memorial Pediatric Abstract Award
    • Toxicology Trainee Research Grant
    • Student and Trainee Travel Award
    • Lampe-Kunkel Memorial Award
  • Resources
    • Event Calendar
    • AACT Mobile App
    • Publications
      • AACTion
      • Abstracts
      • Clinical Toxicology Journal
      • Question of the Day
      • News
      • Current Awareness in Clinical Toxicology
      • Toxicology Today
      • Out of Hospital Guidelines
    • Toxicology Information
    • Affiliated Organizations
    • Press Resources
    • Job Opportunities
    • Online Store
  • About Us
    • Mission & Strategic Plan
    • Board of Trustees
    • Our History
    • Membership
      • AACT Member Directory
    • Award Recipients
    • Contact Us
  • Contact Us
March 7, 2018

Question of the Day – Wednesday March 7, 2018

Question- What is the basis for the neurological damage that may result from the chronic inhalational abuse of toluene?

Answer- The cited reference notes “Results from case studies of toluene abusers suggest that some of the neurological symptoms associated with chronic toluene abuse may be the result of permanent structural changes in the brain. Evaluation of chronic toluene abusers by magnetic resonance imaging (MRI) and single photon emission computed tomography (SPECT) has shown an increase in the white matter signal, a loss of gray and white matter differentiation, and decreased perfusion in the cerebral cortex, basal ganglia, and thalami. Cerebral, cerebellar, and brainstem atrophy were also present. Correlations between clinical signs of neurological impairment and damage visible in MRI images have also been reported. Abnormalities in MRI and brainstem auditory-evoked response (BAER) results were still present in chronic abusers who had refrained from toluene exposure for two to nine months.” (https://www.atsdr.cdc.gov/toxprofiles/tp56-c3.pdf; accessed February 2018)

Posted in Question Of The Day
Share this

Recent Posts

  • Question of the Day – Monday, March 27, 2023
  • Question of the Day – Friday, March 24, 2023
  • Seeking Nominees for 2023 AACT National Election
  • Question of the Day – Thursday, March 23, 2023
  • Question of the Day – Wednesday, March 22, 2023

Site Search

Get Involved

Volunteer for a committee, as a section chair, student chapter mentor, author Question of the Day and more!

Volunteer

Support AACT

Become a ‘Friend of the Academy’ through a tax-deductible financial contribution. Donating is just a text away!

Make a Contribution
aact-footer-logo

American Academy of Clinical Toxicology
6728 Old McLean Village Drive
McLean, VA 22101

Twitter

Privacy Policy

  • Education & Groups
    • American Board of Applied Toxicology (ABAT)
      • ABAT Exceptional Service Award
      • ABAT Newsletter
      • Sitting for the American Board of Applied Toxicology Exam
        • ABAT Examination Study Guide
      • Certification Renewal Documents
      • Life Long Learning Articles (LLSA)
      • ABAT Member Directory
        • Diplomate Verification
      • ABAT Board of Directors Contact Information
    • E-Learning
      • Advanced Hazmat Life Support Training
      • MMTI Fundamentals for Front-Line Practitioners Training
      • TOXISMO Society for the Discussion of Scientific Literature
      • ToxNow
      • Webinars
        • ABAT Journal Club Webinars
        • COVID Webinar Series
    • Toxicology Residency & Fellowship Training Programs
    • Clinical Toxicology Guidelines Collaborative
      • Recommendations
    • Fellows of AACT
    • ToxCoach Mentorship Program
    • Committees
    • Sections
      • Acute & Intensive Care
      • Addiction Toxicology Section
      • Clinical Toxicology In Sports
      • Diversity, Equity, and Inclusion Section
      • Herbs & Dietary Supplements
      • Geriatric Toxicology
      • Occupational / Environmental
      • Envenomations
      • Forensic
      • Pediatric
      • Weapons of Mass Destruction
      • Toxicology History
      • Radiation
      • Trainee and Student
    • Student Chapters
  • NACCT Annual Meeting
    • Meeting Information
    • Abstract Submissions
    • After the Fact CE
  • Research Grants
    • AACT Research Award
    • AACT Knowledge Translation Grant Award
    • Junior Investigator Research Grant
    • Gary S. Wasserman, DO, FAACT Memorial Pediatric Abstract Award
    • Toxicology Trainee Research Grant
    • Student and Trainee Travel Award
    • Lampe-Kunkel Memorial Award
  • Resources
    • Event Calendar
    • AACT Mobile App
    • Publications
      • AACTion
      • Abstracts
      • Clinical Toxicology Journal
      • Question of the Day
      • News
      • Current Awareness in Clinical Toxicology
      • Toxicology Today
      • Out of Hospital Guidelines
    • Toxicology Information
    • Affiliated Organizations
    • Press Resources
    • Job Opportunities
    • Online Store
  • About Us
    • Mission & Strategic Plan
    • Board of Trustees
    • Our History
    • Membership
      • AACT Member Directory
    • Award Recipients
    • Contact Us
  • Contact Us

© 2023 American Academy of Clinical Toxicology | Sitemap

Website by Yoko Co

Scroll To Top