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The American Academy of Clinical Toxicology
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March 13, 2018

Question of the Day – Tuesday March 13, 2018

Question- What is the name of the neurotoxic syndrome occurring in approximately 10% of individuals taking calcineurin inhibitors?

Answer- The “posterior reversible encephalopathy syndrome” occurs in approximately 10% of individuals taking calcineurin inhibitors. The cited reference notes that this syndrome is characterized by “headaches, confusion, vision abnormalities and seizures. While the specific pathophysiology for this syndrome is unknown “endothelial injury and vasogenic edema due to the failure of cerebral autoregulation have been described as a potential mechanism.” (El-Jawahri AR et al. Case 5-2018: A 63-year-old man with confusion after stem cell transplantation. 2018 NEJM 378(7):659-669)

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  • Education & Groups
    • American Board of Applied Toxicology (ABAT)
      • ABAT Exceptional Service Award
      • ABAT Newsletter
      • Sitting for the American Board of Applied Toxicology Exam
        • ABAT Examination Study Guide
      • Certification Renewal Documents
      • Life Long Learning Articles (LLSA)
      • ABAT Member Directory
        • Diplomate Verification
      • ABAT Board of Directors Contact Information
    • E-Learning
      • Advanced Hazmat Life Support Training
      • MMTI Fundamentals for Front-Line Practitioners Training
      • TOXISMO Society for the Discussion of Scientific Literature
      • ToxNow
      • Webinars
        • ABAT Journal Club Webinars
        • COVID Webinar Series
    • Toxicology Residency & Fellowship Training Programs
    • Clinical Toxicology Guidelines Collaborative
      • Recommendations
    • Fellows of AACT
    • ToxCoach Mentorship Program
    • Committees
    • Sections
      • Acute & Intensive Care
      • Addiction Toxicology Section
      • Clinical Toxicology In Sports
      • Diversity, Equity, and Inclusion Section
      • Herbs & Dietary Supplements
      • Geriatric Toxicology
      • Occupational / Environmental
      • Envenomations
      • Forensic
      • Pediatric
      • Weapons of Mass Destruction
      • Toxicology History
      • Radiation
      • Trainee and Student
    • Student Chapters
  • NACCT Annual Meeting
    • Meeting Information
    • Abstract Submissions
    • After the Fact CE
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