Question: Stevens-Johnson’s syndrome and toxic epidermal necrolysis are potentially fatal mucocutaneous diseases that in some cases may be due to a variety of drugs. Which drugs are most commonly implicated as etiologic agents in pediatric patients suffering from these diseases?
Answer: The cited article notes “Antibiotics, anticonvulsants, and nonsteroidal anti-inflammatory drugs are the most commonly implicated etiologies in children.” (Catt CJ et al. Ocular manifestations of Stevens Johnsons syndrome and toxic epidermal necrolysis in children. 2016 Am J Opthalmol. 166:68-75