Question: In patients taking injectable insulin, what is the suspected avcse for insulin-mediated lipohypertrophy?
Answer: The cited reference notes “Insulin-induced lipohypertrophy occurs at the injection site and is thought to be the result of repeated trauma and possibly the anabolic side effects of insulin. The condition can lead to labile control of blood glucose levels owing to variable insulin absorption at these sites. Lipohypertrophy typically causes such palpable, rubbery growths….” (Verma R. Insulin-mediated lipohypertrophy. 2017 NEJM 377(6):573