Administrator Jeanna - Five

Question: MEK inhibitors (inhibit the mitogen- activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) kinase) are a relatively new class of chemotherapeutic agents used in the treatment of a variety of metastatic cancers. These agents have been associated with the development of ocular toxicity. What is the nature of this toxicity?

Question: What is the elimination half-life of smoked crystal methamphetamine?

Question: How do electronic cigarettes produce the vapor inhaled by users of these products?

Question: Lithium is widely used as long-term therapy for bipolar disorder. What are the clinically important adverse risks for patients on long-term lithium therapy?

Question: What does the term “signal word”, as used by U.S. EPA, signify?

Question: What is rotenone?

Question: Which foodborne pathogen accounts for approximately 20 percent of bacterial meningitis in individuals older than 60 years of age and has been associated with unpasteurized milk and soft cheese ingestion?

Question: A variety of clinical forms of botulism have been recognized. These include wound botulism, food borne botulism, and infant botulism. What is the most common form of botulism reported in the United States?

Question: Botulism is an uncommon disorder caused by toxins produced by Clostridium botulinum. Seven subtypes of botulinum toxin exist (subtypes A, B, C, D, E, F and G). Which subtypes have been noted to cause human disease and which ones have been reported to cause infant botulism specifically in the United States?

Question: What are the reported central nervous system manifestations associated with neonatal abstinence syndrome?