Administrator Jeanna - Five

Question: What is the scientific basis for using nails (fingernails and/or toe nails) as a testing matrix for detecting drugs?

Question: Hepatic veno-occlusive disease (HVOD) has been reported as a complication of herbals that contain pyrrolizidine alkaloids. What are the clinical characteristics of hepatic veno-occlusive disease?

Question: What is “iodide mumps”?

Question: Loperamide is an antidiarrheal agent available as an over the counter drug available to the public without a prescription. What is the mechanism by which this drug reduces diarrhea?

Question: What are the factors that affect health care worker exposures to potentially hazardous antineoplastic drugs?

Question: As part of their risk management strategy for certain drugs, the Food and Drug Administration (FDA) requires a so-called “Risk Evaluation and Mitigation Strategy (REMS)”. What does a REMS include?

Question: The concentration of melanin in human hair is recognized as affecting the amount of some drugs that might be incorporated into hair. As a consequence, at co-equal doses, higher drug levels are typically found in the hair of individuals with darker colored hair. This influence is particularly pronounced for which class of drugs?

Question: One population-based cohort study of older adults, observed that new use of an atypical antipsychotic drug was associated with a higher 90-day risk for hospitalization with acute kidney injury (AKI). What are the potential causes for this observed effect?

Question: A recent analysis of counterfeit OxyContin seized in Canada demonstrated fentanyl to be present in 89% of all tablets. Fentanyl is also often found in counterfeit alprazolam as well as other counterfeit medications. Why is fentanyl apparently used so often in the production of…

Question: A recent analysis of counterfeit OxyContin seized in Canada demonstrated fentanyl to be present in 89% of all tablets. Fentanyl is also often found in counterfeit alprazolam as well as other counterfeit medications. Why is fentanyl apparently used so often in the production of illicit street drugs?

Question: What is the “exposome”?