Question of the Day – Thursday September 12, 2019

Question – The article cited below notes “Immune thrombocytopenia (ITP) is an autoimmune disease characterized by isolated thrombocytopenia. Patients may be asymptomatic at presentation or they may present with mild mucocutaneous to life threatening bleeding”. Sudden onset of ITP has been reported after initiation of which medications?

 

 

Answer – Sudden onset of ITP has been reported following the initiation of quinine or quinidine, acetaminophen, abciximab, carbamazepine, rifampicin and vancomycin. (Cooper N and Ghanima W. Immune thrombocytopenia. 2019 NEJM 381(10):945-955