Question of the Day – Monday August 5, 2019

Question – What is the “Ames test” used for?

 

Answer – The cited article notes “The Ames test is used world-wide as an initial screen to determine the mutagenic potential of new chemicals and drugs. The test is also used for submission of data to regulatory agencies for registration or acceptance of many chemicals, including drugs and biocides. International guidelines have been developed for use by corporations and testing laboratories to ensure uniformity of testing procedures.” (Mortelmans K and Zeiger E. The Ames Salmonella/microsome mutagenicity assay. 2000 Mut Res 455(1-2):29-60.