Question of the Day – Wednesday December 27, 2017

Question: What is the association between occupational cadmium exposure and the risk for the development of renal cancer?

Answer: The cited meta-analysis reports “The meta-analysis showed that a high Cd exposure significantly increased renal cancer 1.47 times (OR = 1.47; 95% CI = 1.27 to 1.71, for highest versus lowest category of cadmium categories). The significant association remained consistent when stratified by geographic region and gender, however mixed results were produced when stratified by sample size, study design, NOS score, adjustment for covariates, effects measure, and exposure type. Our results indicated that a high Cd exposure was associated with increased renal cancer risk and the association was higher for occupational exposure compared with non-occupational exposure. This meta-analysis suggests that a high Cd exposure may be a risk factor for renal cancer in occupational population”. (Song J et. al. Association between cadmium exposure and renal cancer risk: a meta-analysis of observational studies. 2015 Sci. Rep. 5, 17976; doi: 10.1038/srep17976)