Question of the Day – Thursday November 2, 2017

Question: What is patiromer?

Answer: The cited reference points out patiromer is “a novel non-absorbed, cation-exchange polymer that binds and exchanges potassium for calcium, predominantly in the gastrointestinal tract. It has demonstrated potassium-lowering effects in normo- or hyperkalemic patients on concomitant RAAS inhibitors with heart failure, diabetic nephropathy, and CKD, in the PEARL-HF, AMETHYST-DN, and OPAL-HK studies, respectively. Across all studies, it appears to be generally effective and well tolerated, with adverse events predominantly gastrointestinal in nature.” Vu BN et al. Patiromer: The first potassium binder approved in over 50 years. 2016 Cardiology in Review 24:316-323.