Question of the Day – Friday December 22, 2017

Question: Chronic exposure to benzene may result in a range of hematopoietic derangements. What are these hematopoietic derangements?

Answer: The cited reference notes “Chronic exposure to benzene leads to a range of hemopoietic malfunctions involving anemia, leucopenia, thrombocytopenia, pancytopenia. Acute myelogenous leukemia is the major cancerous disorder associated with chronic benzene exposure, although other forms of leukemia have also been reported.” (Zolghadr F et al. How benzene and its metabolites affect human marrow derived mesenchymal stem cells. 2012 Tox Letters 214:145-153)