Question of the Day – Wednesday, May 10, 2023
What findings are seen on brain imaging in patients with suspected paradichlorobenzene-induced leukoencephalopathy? Imaging of the brain is standard of care in cases of toxic leukoencephalopathy, but imaging findings in toxic leukoencephalopathy secondary to PDCB consumption are nonspecific and can include involvement of periventricular and…
Question of the Day – Tuesday, May 9, 2023
What tests are useful in the diagnosis of paradichlorobenzene (PDCB) toxicity? High urine concentration of the metabolite 2,5-dichlorophenol, high serum concentrations of PCDB, along with history and signs/symptoms of toxicity often guide the decision making. The diagnosis can be challenging due to overlap in clinical…
Question of the Day – Monday, May 8, 2023
What signs and symptoms are specific for paradichlorobenzene-induced neurotoxicity? According to the cited reference, PDCB toxicity can affect any part of the nervous system and there are no signs or symptoms specific for PDCB-induced neurotoxicity. Clinical manifestations can include psychomotor retardation, cognitive decline, memory issues,…