Question of the Day – Tuesday, May 30, 2023
How do macrolides and tetracyclines affect serum digoxin concentrations? Macrolide antibiotics such as clarithromycin and erythromycin, and tetracyclines such as tetracycline and doxycycine alter the normal flora of the gut, including Eubacterium lentum. Under normal conditions, Eubacterium lentum inactivates digoxin in 10 – 15% of…