This biochemical marker has been theorized to be a predictor of delayed neurologic sequalae after carbon monoxide poisoning.
Netrin-1. Netrin-1 has been previously investigated as a predictive biomarker of neurologic sequalae following both hemorrhagic and ischemic stroke. Kokulu K et al. sought to examine if netrin-1 levels obtained at presentation were predictive of DNS in carbon monoxide poisoning. The authors concluded that low serum netrin-1 concentrations were associated with DNS in patients with unintentional CO poisoning.
Kokulu K et al. Serum netrin-1 levels at presentation and delayed neurological sequelae in unintentional carbon monoxide poisoning. Clin Tox 2020; 58(12):1313-1319.