Question of the Day – Tuesday November 3, 2020
Identify this compound BAL (British Anti-Lewisite), or Dimercaprol https://pubchem.ncbi.nlm.nih.gov/compound/3080#section=2D-Structure
Question of the Day – Monday November 2, 2020
What is Oliceridine? Oliceridine is a novel opioid agonist pain medication that was approved by the FDA in August of 2020 for intravenous use in the controlled clinical setting. https://www.fda.gov/news-events/press-announcements/fda-approves-new-opioid-intravenous-use-hospitals-other-controlled-clinical-settings
Question of the Day – Friday October 30, 2020
What clinical manifestations predict mortality from dinitrophenol exposures reported to poison centers? Acidosis, tachycardia, agitation/confusion, and hyperpyrexia. A retrospective review of dinitrophenol exposures reported to US and UK poison centers identified 204 cases from 2007-2018 with a total of 30 deaths (14.7%). Potts AJ,…
Question of the Day – Thursday October 29, 2020
What agent was associated with the most deaths reported to US poison centers involving exposures from products stored in a secondary container? Hydrofluoric acid. A retrospective study of the National Poison Data System from 2007-2017 identified 45,512 cases reported to US poison centers with…
Question of the Day – Wednesday October 28, 2020
In a recent study published by Thongprayoon C et al, what was the incidence of acute kidney injury in salicylate poisoned patients? Thongprayoon C et al. retrospectively evaluated hospitalized patients with a primary diagnosis of salicylate intoxication from 2003-2014. They found that nearly 10%…
Question of the Day – Tuesday October 27, 2020
What is this? What toxicity is expected? Aniline. Methemoglobinemia. LEE CH et al. Two cases of methemoglobinemia induced by exposure to nitrobenzene and aniline. Ann Occ Environ Med 2013. doi: https://doi.org/10.1186/2052-4374-25-31
Question of the Day – Monday October 26, 2020
A 45 year old female with multiple sclerosis presents to the ED with altered mental status and seizures after an intentional overdose of this medication. What is the medication? 4-aminopyridine (fampridine or dalfampridine). King AM et al. 4-Aminopyridine Toxicity: A Case Report and Review…
Question of the Day – Friday October 23, 2020
What heavy metal caused Minimata disease? Minimata disease, caused by ingestion of methylmercury, occurred in Minimata City in Japan, where inhabitants ingested fish and shellfish contaminated by environmental waste water from a chemical plant. Typical symptoms are primarily neurologic, including sensory and auditory disturbances,…
Question of the Day – Thursday October 22, 2020
Which patient population is most likely to abuse gabapentinoids? According to the cited systematic review, gabapentinoid abuse in the general population has been reported at about 1%, whereas studies of patients with opioid use disorder report gabapentinoid abuse rates between 3 and 68%. Evoy…
Question of the Day – Wednesday October 21, 2020
What type of cancer has been associated with Aristolochic Acid? Urothelial Cancer Gökmen MR, Cosyns JP, Arlt VM, Stiborová M, Phillips DH, Schmeiser HH, Simmonds MS, Cook HT, Vanherweghem JL, Nortier JL, Lord GM. The epidemiology, diagnosis, and management of aristolochic acid nephropathy: a…