Question Of The Day

What is the most common complication of helium inhalation presenting to Emergency Departments in the United States? According to a 20 year review of data obtained from the National Electronic Injury Surveillance System, approxiamtely 2000 helium related injuries present to Emergency Departments Annually in the…

What is a reported complication of soft-tissue augmentation with hyluronic acid? Vascular occulsion has been reported. Patients present with disproportionate pain immediately or several hours after injection. Blanching, livedo or violaceous discoloration has been reported. Hyaluronidase injection has been reported as well as vasodilators and…

What is the mechanism of mamba (Dendroaspis spp.) venom toxicity? α-neurotoxins block postsynaptic nicotinic receptors at the neuromuscular junction, dendrotoxins inhibit voltage-dependent potassium channels which releases acetylcholine at the neuromuscular junction causing a depolarizing effect, fasciculins act as acetylcholinesterase inhibitors, and calciseptine inhibits L-type calcium…

Vitamin C has been used as an alternate reducing agent for methemoglobinemia in individuals with G6PD deficiency. What hematologic complication may arise from the use of high dose vitamin C? An elderly female received a 30 g intravenous dose of vitamin C as a therapy…

What real-time monitoring parameter used for Crotalinae envenomations may aid in the management of venom-induced consumptive coagulopathy? Thromboelastography (TEG) Traditional coagulation parameters have not always been ideal when treating severe coagulopathy from pit viper envenomations and may not identify active fibrinolysis for several hours. TEG…

What antidysrhythmics may be beneficial in the management of ventricular dysrhythmias associated with aconite poisoning? Amiodarone and flecainide. A review of aconite poisoning case reports identified 65 cases reporting ventricular dysrhythmias. Amiodarone was successful in 11 of 20 cases and flecainide was successful in 6…

Occupational exposure to what compound is associated with the radiologic findings pictured? Vinyl chloride is associated with acroosteolysis. Wilson RH, et al. Occupational Acroosteolysis. Jama 1967; 201(8):577-81. doi: 10.1001/jama.201.8.577.  

Occupational exposure to vinyl chloride is associated with development of what type of cancer? Hepatic angiosarcoma. Other potential causes include oral contraceptives, anabolic steroids, radiation, thorium dioxide, and arsenic. Singh G, et al. Heaptic angiosarcoma as a cause of acute liver failure. Case Reports 2018….

What were the most common findings identified in children exposed the methamphetamine? Hypertension and tachycardia. A retrospective review of patients presenting to a pediatric tertiary care center identified 79 patients with suspected methamphetamine toxicity. In addition to typical sympathomimetic findings, common symptoms identified in this…

Nancy Hanks Lincoln, the mother of Abraham Lincoln, died in 1818 due to milk sickness. This occurs after drinking the milk of an animal that has ingested what plant? Snakeroot which contains the toxin tremetol. Milk sickness is characterized by severe gastrointestinal symptoms and was…