Administrator Clintox - One

Serial murder by healthcare professionals is rare. Of the prosecuted cases, which of these specialities had the highest number of prosections: A. Physicians; B. Allied health professionals; C: Respiratory therapists; D: Nursing personnel D. Yorker BC et al. reported that nursing personnel comprised 86% of…

How may a serum lactate level help predict mortality in poisoned patients receiving VA-ECMO? Duburcq T et al., in a retrospective comparison of poisoned patients receiving VA-ECMO, serum lactate > 9 mmol/L predicted mortality with a sensitivity of 0.83 and specificity of 1. A confounder…

In a recent review, what was the median time of a retained bullet to the peak blood lead level? In a recent review by Kershner E et al., 5 years (IQR 0.6. 12) was the median time post exposure to a peak blood level in…

This antidote may be an effective therapy in managing toxicity from Compound 1080. Fomepizole. Compound 1080 is a rodenticide that contains sodium monofluoroacetate and there is animal data that fomepizole reduces oxaloacetate production and therefore may provide a therapeutic benefit. There are no human studies…

Monofluoroacetate has resulted in toxicity in zoo animals and carnivores that have ingested which bird? The Bronzewings (Phaps elegans and Phaps chalcoptera), which are medium sized pigeons native to Australia. Yeung KA et al. Avian Toxins and Poisoning Mechanisms. JMT 2022; 18(321-333)  

What is the theorized toxin responsible for coturnism? Coniine. Ingestion of the European subspecies of migratory quails has resulted in case reports of toxic myopathy with rhabdomyolysis called coturnism. Yeung KA et al. Avian Toxins and Poisoning Mechanisms. JMT 2022; 18(321-333)  

What is one of the toxins that the Blue-capped ifrita has? Homobatrachotoxin. The blue-capped ifrita belongs to the family I. Kowaldi and analysis of its skin and feathers revealed the toxic alkaloid, homobatrachotoxin. Addtional studies have shown that both I. kowaldi and Pitohuis contain a…

What were the most commonly used medications in a review of intentional misuse of veterinary medications in human suicide? Euthanasia preparations, barbiturates, xylazine, acepromazine, tilmicosin Perrin, A. J. “Intentional misuse of veterinary medications in human suicide.” Journal of veterinary pharmacology and therapeutics 38.3 (2015): 209-213….

Common symptoms noted in a 4-Aminopyridine toxicity case report by King et. al, and other published case reports include? Profound diaphoresis, extrapyramidal symptoms, and delirium. King, Andrew M., et al. “4-aminopyridine toxicity: a case report and review of the literature.” Journal of Medical Toxicology 8.3…

What toxidrome does Xylazine toxicity commonly present as? Opioid toxidrome Ball, Noah S., et al. “Xylazine poisoning: a systematic review.” Clinical Toxicology (2022): 1-10. Contributed by: Florida/USVI Poison Information Center-Jacksonville Toxicology Fellowship