Administrator Clintox - One

For a person who injects heroin (diacetylmorphine) and develops toxicity requiring intervention, what is the time interval to need for intervention such as ventilatory support (bag-valve mask) or naloxone? In the Medically Supervised Injecting Room in Melbourne, Australia with 60,693 supervised visits in one year,…

A 2022 review examining lead toxicity from retained bullets found what characteristic of the bullet to influence lead toxicity? If the bullet is jacketed or unjacketed. “Lead absorption from a RB also depends on the type of bullet present. Bullets are commonly composed of an…

Historical QOD 10/09/08: True or False? Sodium azide is responsible for facial and ocular injury due to automobile airbag deployment. False. An alkali aerosol containing sodium hydroxide and sodium carbonate is released into the passenger compartment of the car on airbag deployment. (Can Med J,…

In a recent review of cases of Amanitin intoxication, what laboratory values were found to be possible predictors of potentially fatal outcomes? AST, ALT, Total serum bilirubin, and INR values Tan JL, Stam J, van den Berg AP, van Rheenen PF, Dekkers BGJ, Touw DJ….

Which antidote is pictured below? Prussain blue. https://www.acs.org/content/acs/en/molecule-of-the-week/archive/p/prussian-blue.html  

What percentage of labelled cannabis packages in NYC were found to conform to the American College of Medical Toxicology’s (ACMT) recommendations for safety labelling? Zero. Adam Blumenberg (2022) A cross-sectional assessment of package labels aimed at children of edible and leaf cannabis discarded in New…

Historical QOD 10/8/08: Which drugs have been implicated in the development of diffuse alveolar hemorrhage (DAH) syndrome? Drugs used in the treatment of collagen vascular diseases, such as D-penicillamine reportedly can cause DAH. Cleveland Clinic Journal of Medicine, 2008, 75(4): 258-280  

What was the frequency of precipitated opioid withdrawal when 1.6 mg of IM nalxoone was used to reverse opioid overdose? In a recent prospective review of 171 patients with opioid overdose in Australia, nearly 40% of patients developed acute precipiated withdrawal when administred 1.6 mg…

This alkaloid has been shown to prevent or decrease peripheral neuropathy in rats given paclitaxel likely due to actions on the spinal glycine receptor. What is the alkaloid? Gelsemine. Vitet L et al. Beneficial effects of Gelsemium based treatment against paclitaxel induced painful symptoms. Neurological…