Question of the Day – Tuesday May 4, 2021
Veratrum toxicity is reported after inadvertent ingestion of Veratrum viride (false hellebore) mistaken for which plant? Allium tricocca (ramps or wild leeks). A case report describes accidental ingestion resulting in vomiting, paresthesias, diaphoresis, bradycardia, and hypotension. The patient recovered approximately 8 hours post-ingestion with supportive…
Question of the Day – Monday May 3, 2021
What is the suspected mechanism of carbapenem-induced reduction in valproic acid serum concentrations? Acylpeptide hydrolase inhibition. Valproic acid is conjugated with glucuronic acid in the liver and excreted in bile. Acylpeptide hydrolase in the gastrointestinal tract removes glucuronic acid causing reabsorption of valproic acid and…
Question of the Day – Friday April 30, 2021
What is the most common complication of helium inhalation presenting to Emergency Departments in the United States? According to a 20 year review of data obtained from the National Electronic Injury Surveillance System, approxiamtely 2000 helium related injuries present to Emergency Departments Annually in the…
Question of the Day – Thursday April 29, 2021
What is a reported complication of soft-tissue augmentation with hyluronic acid? Vascular occulsion has been reported. Patients present with disproportionate pain immediately or several hours after injection. Blanching, livedo or violaceous discoloration has been reported. Hyaluronidase injection has been reported as well as vasodilators and…
April Message from AACT President, Dr. Kirk Cumpston
April 28, 2021 With COVID-19 and social injustice occupying our minds so frequently because of the news and social media, we may or may not realize how much stress these issues have placed on our mental health. I know they influence my life every day….
Question of the Day – Wednesday April 28, 2021
What is the mechanism of mamba (Dendroaspis spp.) venom toxicity? α-neurotoxins block postsynaptic nicotinic receptors at the neuromuscular junction, dendrotoxins inhibit voltage-dependent potassium channels which releases acetylcholine at the neuromuscular junction causing a depolarizing effect, fasciculins act as acetylcholinesterase inhibitors, and calciseptine inhibits L-type calcium…
Question of the Day – Tuesday April 27, 2021
Vitamin C has been used as an alternate reducing agent for methemoglobinemia in individuals with G6PD deficiency. What hematologic complication may arise from the use of high dose vitamin C? An elderly female received a 30 g intravenous dose of vitamin C as a therapy…
Question of the Day – Monday April 26, 2021
What real-time monitoring parameter used for Crotalinae envenomations may aid in the management of venom-induced consumptive coagulopathy? Thromboelastography (TEG) Traditional coagulation parameters have not always been ideal when treating severe coagulopathy from pit viper envenomations and may not identify active fibrinolysis for several hours. TEG…
Question of the Day – Friday April 23, 2021
What antidysrhythmics may be beneficial in the management of ventricular dysrhythmias associated with aconite poisoning? Amiodarone and flecainide. A review of aconite poisoning case reports identified 65 cases reporting ventricular dysrhythmias. Amiodarone was successful in 11 of 20 cases and flecainide was successful in 6…
Question of the Day – Thursday April 22, 2021
Occupational exposure to what compound is associated with the radiologic findings pictured? Vinyl chloride is associated with acroosteolysis. Wilson RH, et al. Occupational Acroosteolysis. Jama 1967; 201(8):577-81. doi: 10.1001/jama.201.8.577.